Pediatric Long COVID

10 Pediatric Long COVID

Learning Objectives

Describe the clinical spectrum of pediatric Long COVID, including common neurologic, autonomic, cardiopulmonary, and functional manifestations
Explain proposed pathophysiologic mechanisms underlying pediatric Long COVID, including immune dysregulation, autonomic dysfunction, and post-infectious inflammatory responses
Understand current clinical management approaches for pediatric Long COVID and complications such as dysautonomia or neurocognitive impairment

Faculty:

Sindhu Mohandas, MD – Assistant Professor of Clinical Pediatrics at University of Southern California
Hector Bonilla, MD – Professor of Medicine (Infectious Diseases) at Stanford University School of Medicine
Anita Chopra, MD – Internal Medicine at University of Washington

Students:

AAPM&R Guidelines: Cheng AL, Herman E, Abramoff B, et al. Multidisciplinary collaborative guidance on the assessment and treatment of patients with Long COVID: A compendium statement. PM&R. 2025; 17(6): 684-708. doi:10.1002/pmrj.13397
Rao S, Gross RS, Mohandas S, Stein CR, Case A, Dreyer B, Pajor NM, Bunnell HT, Warburton D, Berg E, Overdevest JB, Gorelik M, Milner J, Saxena S, Jhaveri R, Wood JC, Rhee KE, Letts R, Maughan C, Guthe N, Castro-Baucom L, Stockwell MS. Postacute Sequelae of SARS-CoV-2 in Children. Pediatrics. 2024 Mar 1;153(3):e2023062570. doi: 10.1542/peds.2023-062570. PMID: 38321938; PMCID: PMC10904902.
Gross RS, Thaweethai T, Kleinman LC, Snowden JN, Rosenzweig EB, Milner JD, Tantisira KG, Rhee KE, Jernigan TL, Kinser PA, Salisbury AL, Warburton D, Mohandas S, Wood JC, Newburger JW, Truong DT, Flaherman VJ, Metz TD, Karlson EW, Chibnik LB, Pant DB, Krishnamoorthy A, Gallagher R, Lamendola-Essel MF, et al.; RECOVER-Pediatrics Consortium; RECOVER-Pediatrics Group Authors. Characterizing Long COVID in Children and Adolescents. JAMA. 2024 Aug 21;332(14):1174–88. doi: 10.1001/jama.2024.12747. Epub ahead of print. PMID: 39196964; PMCID: PMC11339705.