8 Neuropsychiatric Complications of Long COVID
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Learning Objectives
- Describe common psychiatric and neuropsychiatric manifestations of Long COVID and differentiate these from primary psychiatric disorders
- Explain proposed biologic and psychosocial mechanisms contributing to psychiatric symptoms in Long COVID, including neuroinflammation, autonomic dysfunction, and functional impairment
- Develop a multidisciplinary management approach to psychiatric complications of Long COVID that integrates pharmacologic treatment, rehabilitation strategies, and patient-centered communication
Video Module: Neuropsychiatric Complications of Long COVID
Faculty:
- Jacob S. Ballon, MD – Associate Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology) at Stanford University School of Medicine
- Hector Bonilla, MD – Professor of Medicine (Infectious Diseases) at Stanford University School of Medicine
- Anita Chopra, MD – Internal Medicine at University of Washington
Students:
- Hollis du Pont – Stanford University
- Tom Quach – Stanford University
Additional Resources & Further Reading
- AAPM&R Guidelines: Cheng AL, Herman E, Abramoff B, et al. Multidisciplinary collaborative guidance on the assessment and treatment of patients with Long COVID: A compendium statement. PM&R. 2025; 17(6): 684-708. doi:10.1002/pmrj.13397
- Caliman-Sturdza OA, Gheorghita R, Lobiuc A. Neuropsychiatric Manifestations of Long COVID-19: A Narrative Review of Clinical Aspects and Therapeutic Approaches. Life (Basel). 2025 Mar 11;15(3):439. doi: 10.3390/life15030439. PMID: 40141784; PMCID: PMC11943530.
Self-Assessment
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