5 Cardiovascular Complications of Long COVID
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Learning Objectives
- Be able to recognize common cardiovascular sequelae of chronic SARS-CoV-2 infection (Long COVID)
- Understand current hypotheses underlying the pathophysiology of Long COVID cardiovascular complications
- Identify strategies for diagnosis and treatment of Long COVID cardiovascular complications
Video Module: Cardiovascular Complications of Long COVID
Faculty:
- Phillip C. Yang, MD – Professor of Medicine (Cardiovascular Medicine) at Stanford University School of Medicine
Students:
- Carissa Lee – University of Washington School of Medicine
- Amogha Paleru – Stanford University
- Mehr Grewal – University of Washington
Additional Resources & Further Reading
- AAPM&R Guidelines: Cheng AL, Herman E, Abramoff B, et al. Multidisciplinary collaborative guidance on the assessment and treatment of patients with Long COVID: A compendium statement. PM&R. 2025; 17(6): 684-708. doi:10.1002/pmrj.13397
- Thomas D, Yang PC, Wu JC, Sayed N. Decoding long COVID-associated cardiovascular dysfunction: Mechanisms, models, and new approach methodologies. J Mol Cell Cardiol. 2025 Sep 30;209:37-50. doi: 10.1016/j.yjmcc.2025.09.008. Epub ahead of print. PMID: 41038267; PMCID: PMC12574943.
- Gunturkun F, Hedlin H, Botzheim B, Deng Y, Bonilla H, Jagannathan P, Quach TC, Kim S, Lin M, O’Riordan G, Tzeng H, Adamowicz L, Demanuele C, Cai X, Yang PC, Singh U, Geng LN. Digital Biometric Measures in Long COVID: A Secondary Analysis of the STOP-PASC Randomized Clinical Trial. JAMA Netw Open. 2025 Aug 1;8(8):e2526901. doi: 10.1001/jamanetworkopen.2025.26901. PMID: 40810942; PMCID: PMC12355292.
Self-Assessment
Test your knowledge with the following quiz questions: